ε-Polylysine (ε-poly-L-lysine) is produced by the fermentation of Streptomyces albulus. • It has high antibacterial activity when its molecular weight is between 3600-4300, but loses activity when its molecular weight is less than 1300. • Pale yellow powder, hygroscopic, almost odorless is an ideal natural antimicrobial to prolong the shelf life, with a high natural antimicrobial activity against a wide range of fungi, Gram-positive and Gram-negative bacteria, and their spores. ε -Polylysine is a homopolymer that consists of 25-35 L-lysine residues. It's produced by a fermentation process using Streptomyces albulus under aerobic conditions. Consumers become more health conscious, and there is an increasing demand for natural preservatives. ε -Polylysine is now gaining some attention for the food industry due to its unique properties including heat stability and excellent antimicrobial activity. ε-Polylysine is food grade and meets FAO/WHO specifications. It is certified as GRAS (Generally Recognized As Safe) by the US FDA with US GRAS No.: GRN000135. Currently, ε-Polylysine has approval as a food additive in China, Korea, Japan, USA and some more countries